Crystal structure of an antifreeze protein from snow mold fungi
نویسندگان
چکیده
منابع مشابه
Ice-binding site of snow mold fungus antifreeze protein deviates from structural regularity and high conservation.
Antifreeze proteins (AFPs) are found in organisms ranging from fish to bacteria, where they serve different functions to facilitate survival of their host. AFPs that protect freeze-intolerant fish and insects from internal ice growth bind to ice using a regular array of well-conserved residues/motifs. Less is known about the role of AFPs in freeze-tolerant species, which might be to beneficiall...
متن کاملCrystal structure of an insect antifreeze protein 1 Crystal Structure of an Insect Antifreeze Protein and its Implications for Ice Binding*
1 Department of Molecular Biophysics & Biochemistry, Yale University, New Haven, CT 06520 2 Department of Molecular, Cellular & Developmental Biology, Yale University, New Haven, CT 06520 3 Department of Biomedical & Molecular Sciences, Queen’s University, Kingston, ON K7L 3N6, Canada 4 Systems Biology Institute, Yale University, West Haven, CT 06516 5 These authors contributed equally to the work
متن کاملCrystal structure of an insect antifreeze protein and its implications for ice binding.
Antifreeze proteins (AFPs) help some organisms resist freezing by binding to ice crystals and inhibiting their growth. The molecular basis for how these proteins recognize and bind ice is not well understood. The longhorn beetle Rhagium inquisitor can supercool to below -25 °C, in part by synthesizing the most potent antifreeze protein studied thus far (RiAFP). We report the crystal structure o...
متن کاملStudy Examines Snow Mold Solutions for Northwest
Pink snow mold (Mirodochium patch) and gray snow mold [Typhula blight) are the most prevalent and destructive winter diseases on cool-season turfgrass in the northern United States. They are especially destructive in the Intermountain Northwest where deep snow cover may last four to five months. Pentachloronitrobenzene (PCNB, Quintozene) has been use to manage these diseases in turf on golf cou...
متن کاملStructural basis for the superior activity of the large isoform of snow flea antifreeze protein.
The snow flea (Hypogastrum harveyi) is protected from freezing at sub-zero temperatures by a glycine-rich antifreeze protein (AFP) that binds to seed ice crystals and prevents them from growing larger. This AFP is hyperactive and comprises two isoforms [Graham, L. A., and Davies, P. L. (2005) Science 310, 461]. The larger isoform (15.7 kDa) exhibits several-fold higher activity than the smaller...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Acta Crystallographica Section A Foundations of Crystallography
سال: 2008
ISSN: 0108-7673
DOI: 10.1107/s010876730808820x